Tuesday, April 30, 2013

Holocaust survivors, veterans gather at DC museum

WASHINGTON (AP) ? Elderly survivors of the Holocaust and the veterans who helped liberate them gathered for what could be their last big reunion Monday at the U.S. Holocaust Memorial Museum.

One thousand survivors and World War II vets joined with former President Bill Clinton and Nobel Peace Prize laureate and Holocaust activist Elie Wiesel to mark the museum's 20th anniversary. Organizers chose not to wait for the 25th milestone because many survivors and vets may not be alive in another five or 10 years.

"We felt it was important, while that generation is still with us in fairly substantial numbers, to bring them together," said Museum Director Sara Bloomfield.

Washington has many monuments and memorials that offer something special for visitors from around the world, "but the Holocaust memorial will be our conscience," Clinton said.

Since the museum opened 20 years ago, the world has made huge scientific discoveries, including the sequencing of the human genome, which proved humans are 99.5 percent genetically the same, Clinton said.

"Every non age-related difference ... is contained in one half of 1 percent of our genetic makeup, but every one of us spends too much time on that half a percent," Clinton said. "That makes us vulnerable to the fever, the sickness that the Nazis gave to the Germans. That sickness is very alive across the world today."

The occasion marked a reunion of sorts for Clinton and Wiesel as well: Both were on hand to dedicate the museum at its opening in 1993. On Sunday night, the museum presented its highest honor to World War II veterans who helped end the Holocaust. Susan Eisenhower accepted the award on behalf of her grandfather, U.S. Gen. Dwight D. Eisenhower, and all veterans of the era.

The museum also launched a campaign to raise $540 million by 2018 to keep the memory of the Holocaust alive and to combat anti-Semitism, Holocaust denial and contemporary genocide. It has already secured gifts totaling $258.7 million. The campaign aims to double the size of the museum's endowment by its 25th anniversary. Also, a $15 million gift from Holocaust survivors David and Fela Shapell will help build a new collections and conservation center.

Bloomfield said organizers wanted to show Holocaust survivors, veterans and rescuers that the effort will continue to honor the memory of 6 million murdered Jews, in part by working to prevent genocide in the future.

Vera Greenwood, who was born in Berlin and remembers as a girl seeing Hitler with Nazis marching in the street, said her father knew they had to leave when he was forced out of his job as a lawyer. She remembers Nazi officers coming to their house and taking her father's books.

"Though I was very young, I knew something was very wrong," said Greenwood, now 84. "I still feel we were very lucky to survive."

Her family moved to Palestine with a British visa and ended up fighting for Israel's independence. Greenwood lived in Israel for 30 years before immigrating to the U.S. and completing a doctorate at Arizona State University.

She and her husband, Fred, who survived the Holocaust in Holland as a child by being hidden and passed from house to house, wanted to be part of the last large reunion of survivors.

"In 10 more years, most of us will be gone," Greenwood said.

The museum continues collecting objects, photographs and other evidence of the Holocaust from survivors, veterans and archives located as far away as China and Argentina. Curators expect the collection to double in size over the next decade.

This week, the museum is opening a special, long-term exhibit titled "Some Were Neighbors: Collaboration and Complicity During the Holocaust." It includes interviews with perpetrators that have never been shown before, as well as details of mass killings in the former Soviet Union that were only uncovered in more recent years.

Curator Susan Bachrach said the exhibit and its research challenge the idea that the Holocaust was primarily about Hitler and other Nazi leaders. Surveys at the museum show that's what most visitors believe.

"That's very comforting to people, because it puts distance between the visitors and who was involved," Bachrach said.

So, the museum set out to look at ordinary people who looked on and were complicit in the killing and persecution of millions of Jews through greed, a desire for career advancement, peer pressure or other factors. It examines influences "beyond hatred and anti-Semitism," Bachrach said.

Focusing only on fanatical Nazis would be a serious misunderstanding of the Holocaust, Bloomfield added.

"The Holocaust wouldn't have been possible, first of all, without enormous indifference throughout Germany and German-occupied Europe, but also thousands of people who were, say, just doing their jobs," she said, such as a tax official who collected special taxes levied against Jews.

In an opening film, some survivors recall being turned over to Nazi authorities in front of witnesses who did nothing. "The whole town was assembled ... looking at the Jews leaving," one survivor recalls.

Steven Fenves was a boy at the time. He recalled how in 1944, the government of Hungary, allied with Nazi Germany, forced his family out of its apartment. The family was deported to Auschwitz, where Fenves' mother was gassed.

"One of the nastiest memories I have is going on that journey and people were lined up, up the stairs, up to the door of the apartment, waiting to ransack whatever we left behind, cursing at us, yelling at us, spitting at us as we left," he said in an interview with the museum.

The museum located images of bystanders looking on as Jews were detained, humiliated and taken away.

Non-Jews were also punished for violating German policies against the mixing of ethnic groups. For the first time, the museum is showing striking, rare footage of a ritualistic shaming of a Polish girl and a German boy for having a relationship. They are marched through the streets of a town in Poland, where the film was located in an attic. Dozens of people look on as Nazi officers cut the hair of the two teenagers. They are forced to look at their nearly bald heads in a mirror before their hair is burned.

The federally funded museum's theme for its 20th anniversary is "Never Again: What You Do Matters." The museum devotes part of its work and research to preventing future genocides. A study released by the museum last month found that the longer the current conflict in Syria continues, the greater the danger that mass sectarian violence results in genocide.

Much more is still being learned about the Holocaust, as well, Bloomfield said. The museum is compiling an encyclopedia of all incarceration sites throughout Europe. When the project began, scholars expected to list 10,000 such sites. Now the number stands at 42,000.

Since opening, the museum has had more than 35 million visitors.

___

U.S. Holocaust Memorial Museum: http://www.ushmm.org

___

Follow Brett Zongker on Twitter at https://twitter.com/DCArtBeat

Source: http://news.yahoo.com/holocaust-survivors-veterans-gather-dc-museum-095000298.html

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White House commends Jason Collins on coming out

(AP) ? The White House is commending NBA veteran Jason Collins for becoming the first active male player in the four major American professional sports to come out as gay.

White House spokesman Jay Carney called that decision courageous and says the White House supports Collins. He says he hopes the 34-year-old center's team will also offer support.

Carney says the White House views Collins' decision as another example of progress and evolution in the U.S. as Americans grow more accepting of gay rights and same-sex marriage. Last year, during his re-election campaign, Obama announced his support for gay marriage.

Collins disclosed he was gay Monday in a first-person account posted on Sports Illustrated's website. He has played for six teams in 12 seasons, including this past season with the Washington Wizards.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-29-Jason%20Collins-Obama/id-d4afabd2ea94487b834b25c7cfce5a02

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Monday, April 29, 2013

One year on, France's Hollande says will weather poll slump

By Elizabeth Pineau

PARIS (Reuters) - France's Francois Hollande said he was undeterred by a first year in power marked by economic slowdown and a record slump in his personal popularity, arguing his 5-year presidency would achieve results over time.

In comments to correspondents from Reuters and Agence France Presse a week before the anniversary of his May 2012 election win over Nicolas Sarkozy, Hollande shrugged off polls showing his popularity rating around 25 percent, after the sharpest fall for any president in over half a century.

"I'm aware how serious the situation is. It's a president's duty to stay the course and to look beyond today's squalls. It's called perseverance," Hollande said.

"People can criticize my decisions, think I am on the wrong track or have not taken the right route, but if there is one thing I am sure of it's that I have taken major decisions for France - many more in 10 months than were taken in 10 years."

Hollande, France's first Socialist president since Francois Mitterrand, is squeezed between a business sector clamoring for lower taxes and labor costs, euro zone partners pressing for budget cuts and households hostile to austerity measures.

He said he would persevere with measures to restore growth like corporate tax credits aimed at easing headcount costs and a labor reform set to become law in May.

"It's the president who is held to account, and that's quite legitimate. It's up to me to weigh up what I need to do for the country today. To remain in control by being sure of my ideas."

RALLY THE NATION

After his campaign pledges to revive the flagging industrial sector, end a relentless rise in unemployment and meet deficit-cutting targets, Hollande has had to row back on almost all his economic targets, as factory layoffs continue apace.

While he stands by a goal to turn around unemployment by year-end, few believe he can achieve that. Jobless claims rose for the 23rd straight month in March to an all-time high.

Treading a delicate line as he attempts step-by-step reforms that were not part of his election campaign, Hollande said the country should have faith in him.

"The only thing that counts is the results. I have made promises and I will be judged on them," he said. "My hope is to rally the nation and restore confidence. That will take time, but it's my sole objective."

His economic woes aside, Hollande is also suffering from a perception that since he took power France is losing its voice on European policy. His prime minister said this month that France was losing its leadership role.

Foreign investors are watching closely since the government admitted it would need an extra year to reach a European Union budget deficit ceiling of 3 percent of output.

Inside France, where a scandal over an ex-budget minister's secret Swiss bank account has not helped, polls show a slim majority of people would prefer Sarkozy to be president today.

"I realized a long time ago that I would not go far if I let the commentary get to me," Hollande said. "According to what was said about me as a candidate, I had no chance of becoming president."

(Writing by Catherine Bremer; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/one-frances-hollande-says-weather-poll-slump-081408823.html

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Ashton Kutcher?s Violent Fight At Stagecoach Festival

Ashton Kutcher’s violent fight at Stagecoach Music Festival is making headlines today after he got into a serious altercation with a security guard. However was it really his fault or was he actually defending himself and a fan? The Stagecoach Music Festival took place this weekend in Indio, California. It is the festival dedicated to Country Music, brining some of the genre’s biggest stars as well as up and comers. TMZ was first to break the story that Kutcher, dressed the part of a country fan in a cowboy hat and white t-shirt, got into a serious fight with a security guard at the event. According to the website the actor was watching Nick 13 and Dwight Yoakam, in the VIP area of course, when a female fan approached. The story goes that when he turned to greet the fan, a couple of security guards intervened and shoved the two of them. This clearly did not go over well with Ashton and it became mass mayhem. Allegedly the That 70′s Show alum and the security got into a very violent shoving match, that was only resolved when Kutcher’s friends restrained him. Despite the security guard demanding that Ashton be kicked [...]

Source: http://feedproxy.google.com/~r/RightCelebrity/~3/vaJbvTZ4zlI/

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Sunday, April 28, 2013

Biden: Economy kept McCain from victory over Obama

SEDONA, Ariz. (AP) ? Vice President Joe Biden said Friday that Arizona Sen. John McCain probably would have beat his boss in the 2008 presidential election had the economy not collapsed.

Biden's comment about McCain and President Barack Obama came during the opening dinner of an annual forum among the Red Rocks of Sedona in northern Arizona. He and McCain, a Republican, touched on the gun control debate following the Newtown shootings and the bombings in Boston, but made no mention of Syria. Just as the night came to a close, Biden turned to the grueling nature of presidential campaigns.

"The truth of the matter is, Barack knows it, I know, had the economy not collapsed around your ears, John, in the middle of literally ? as things were moving ? I think you probably would have won," Biden said. "But it would have been incredibly, incredibly, incredibly close. You inherited a really difficult time."

The forum is part of the McCain Institute for International Leadership, a program formed by McCain as a way to debate foreign affairs. This year's theme for the Sedona Forum is "How can we promote freedom and democracy effectively?"

Rather than a discussion between McCain and Biden, the two sat on stage together with McCain posing questions to his former Democratic adversary on gun control and whether background checks are necessary, human rights abuses at the hands of the United States and the recent bombings at the Boston marathon.

McCain and Biden both said that despite their disagreements, they've never lost respect for one another.

On gun control, Biden said it's never been a simple issue, but that Congress has miscalculated how deeply the public feels about it and has failed to stand up to groups like the National Rifle Association, particularly after the shootings in Newtown. He said the public is looking to Congress to be mature enough to figure out a way to diminish the chance it will happen again.

"For the first time ever, you have people who are for gun safety, for increasing background checks," Biden said. "Two out of three of them say it will be a major determining factor in how I vote. That's the political dynamic that has changed. So I think we're going to get this anyway. I think this will pass before the year is out, within this Congress."

In responding to a question about the vulnerabilities of the United States when it comes to terrorist attacks, Biden said that the radical, lone wolves have been the most difficult to catch. But he said America shouldn't change its values, how it treats people abroad or people coming into the United States. Nor should America adopt policies that keep people from freely walking down the street without being frisked by police or carrying identification cards, he said.

"The moment we change any of those things, that's when they win," Biden said. "Because they don't see how you can have a society that is not ordered and regimented and wedded to an orthodoxy that is theirs. That's the point that bothers them most about us."

McCain followed up by saying that those who tortured U.S. prisoners, in violation of the Geneva convention, should be exposed and be held responsible to prevent repeated abuses.

Biden agreed with the man once held as a prisoner of war during the Vietnam War. He said the internal debate in Congress and at the White House is how things got to that point, but it's not yet resolved.

"I think the only way you excise the demons is you acknowledge what happened, straightforward," Biden said.

Source: http://news.yahoo.com/biden-economy-kept-mccain-victory-over-obama-050052639.html

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Have a Seat: This Chair Was Made From Compost (VIDEO)

In this era of recycle, reuse, reduce, the trend in personal goods has been to prevent as much of it as possible from ending up in a landfill.? What was once garbage is now the source material for electric appliances, bicycles and even play structures.

And while that concept isn?t new, using actual dirt and molding it into the shape of furniture is certainly new. Or, it?s so old it?s new to us.

Terra is a company that uses compost, made up of 100 percent organic materials like soil, manure and plant matter, and using ancient techniques, fashions it into cool modern furniture.

Israeli designer, Adital Ela is a self-described ?designer-gatherer? and the creator of Terra?s biomaterial furniture line. After a lengthy research project, Ela blended ancient practices from places like Palestine and Iraq with a few modern production techniques, to come up with her unique mixing formula?some of which does involve foot-stomping.

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All of Terra?s pieces are made using zero energy and can be replicated anywhere organic waste is available. They?re also fully renewable and biodegradable: The stools, cups and the rest of the line's pieces can all be smashed and returned to the Earth once they?ve outlived their use.

As she explains in her TED talk, Ela first became enamored with the idea in India, when she was served a cup of chai in a sun-dried, clay mug. ?I was absolutely fascinated by the way the locals gulped down this delicious boiling drink, tossing the cups into the ground?The cups, made of clay, dried by the sun, touched the Earth, and blended with it and within minutes, they disappeared,? she said. ?Seeing this?I started asking myself, 'How can products, like people, come from dust, and to dust return?'?

But Terra is only one in a portfolio of Ela?s many sustainable green designs. She?s the founder and director of S-Sense, an Israeli firm that?s also created artful residential rainwater collectors, wind-powered garden lights, and colorful textiles made from secondhand clothes.

While the furniture might be looked upon by some as more of a novelty, Ela's entire body of work is the sign of a person dedicated to using her business in a way that positively impacts the world around her.

Would you buy stools made from compost? Let us know what you think of Terra in the Comments.

Related Stories on TakePart:

? This Little Teapot Was Made From Garbage

? Op-Ed: The Dawn of a Sub-Saharan Solar Revolution

? Hawaii?s Solar Market Is Booming; Why This Is a Very Bad Thing


A Bay Area native, Andri Antoniades previously worked as a fashion industry journalist and medical writer.??In addition to reporting the weekend news on TakePart, she volunteers as a webeditor for locally-based nonprofits and works as a freelance feature writer for?TimeOutLA.com. Email Andri | @andritweets?| TakePart.com

Source: http://news.yahoo.com/seat-chair-made-compost-video-003833869.html

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Six months after Sandy, thousands homeless in N.Y., N.J.

MANTOLOKING, N.J. (AP) ? The 9-year-old girl who got New Jersey's tough-guy governor to shed a tear as he comforted her after her home was destroyed is bummed because she now lives far from her best friend and has nowhere to hang her One Direction posters.

A New Jersey woman whose home was overtaken by mold still cries when she drives through the area. A New York City man whose home burned can't wait to build a new one.

Six months after Superstorm Sandy devastated the Jersey shore and New York City and pounded coastal areas of New England, the region is dealing with a slow and frustrating, yet often hopeful, recovery. Tens of thousands of people remain homeless. Housing, business, tourism and coastal protection all remain major issues with the summer vacation ? and hurricane ? seasons almost here again.

"Some families and some lives have come back together quickly and well, and some people are up and running almost as if nothing ever happened, and for them it's been fine," New York Gov. Andrew Cuomo said at a news conference Thursday. "Some people are still very much in the midst of recovery. You still have people in hotel rooms, you still have people doubled up, you still have people fighting with insurance companies, and for them it's been terrible and horrendous."

Lynda Fricchione's flood-damaged home in the Ortley Beach section of Toms River, N.J., is gutted; the roof was fixed just last week. The family is still largely living out of cardboard boxes in an apartment. But waiting for a final decision from federal and state authorities over new flood maps that govern the price of flood insurance is tormenting her and many others.

"The largest problem is, nobody really knows how high we're going to have to elevate the house," she said. "At town hall they told us 5 feet, but then they said it might go down to 3 feet in the summer. Most of us are waiting until the final maps come out. It's wait-and-see."

But more than anything, Fricchione is optimistic, buoyed by a recent trip to New Orleans with her daughter during which they met a resident of the Lower Ninth Ward who was one of the first to move back in after Hurricane Katrina inundated the neighborhood that has become a symbol of flood damage ? and resilience.

"Talking to that man was wonderful!" Fricchione said. "He said it takes time and you just have to have hope and know it will all work out eventually."

By many measures, the recovery from Superstorm Sandy, which struck Oct. 29, has been slow. From Maryland to New Hampshire, the National Hurricane Center attributes 72 deaths directly to Sandy and 87 others indirectly from causes such as hypothermia due to power outages, carbon monoxide poisoning and accidents during cleanup efforts, for a total of 159.

The roller coaster that plunged off a pier in Seaside Heights, N.J., is still in the ocean, although demolition plans are finally moving forward. Scores of homes that were destroyed in nearby Mantoloking still look as they did the day after the storm ? piles of rubble and kindling, with the occasional bathroom fixture or personal possession visible among the detritus.

Throughout the region, many businesses are still shuttered, and an already-tight rental market has become even more so because of the destruction of thousands of units and the crush of displaced storm victims looking to rent the ones that survived.

Homeowners are tortured by uncertainty over ever-changing rules on how high they'll need to rebuild their homes to protect against the next storm; insurance companies have not paid out all that many homeowners expected; and municipalities are borrowing tens of millions of dollars to keep the lights on, the fire trucks running and the police stations staffed, waiting for reimbursement from the federal government for storm expenditures they had to fund out of pocket.

And yet, by other measures, remarkable progress has been made. Boardwalks, the tourism lifeblood of the region, are springing back to life. A handful of homes are going up, and the whine of power saws and the thwack of hammers is everywhere in hard-hit beach towns as contractors fix what can be saved and bulldozers knock down what can't.

Volunteers in Highlands, N.J., are rebuilding the home of Bromlyn Link, the single mother of a 17-year-old boy, both of whom are members of the town's first aid squad and who spent 12 to 14 hours a day helping friends and neighbors forced to live in shelters for weeks after the storm.

Mantoloking, which was cut in half by the storm and saw all 521 of its homes damaged or destroyed, is creeping back to life. The post office recently, reopened, and the first of 50 demolitions will start next week, which is also when Mayor George Nebel will join the 40 other residents who have been able to move back home.

Beaches that were washed away are coming back, due both to nature and bulldozers, and real estate agents say demand for this strangest of upcoming summers appears good, particularly in the large portions of the Jersey shore that were relatively unscathed by Sandy. Beach badges, required for access to most of New Jersey's shoreline, are selling at a near-record pace in Belmar, N.J.

And while towns fortify beaches and dunes and put up sea walls, rock barriers or even sand-filled fabric tubes to guard against future storms, state governments are readying hundreds of millions of dollars to buy out homeowners in flood-prone areas who want to leave.

"We've made a lot of progress in six months; I know we still have a long way to go," New Jersey Gov. Chris Christie said at a recent town hall meeting. "By Memorial Day, every boardwalk that was destroyed at the Jersey shore will be rebuilt. Businesses are reopening. Rentals are picking up again, roads are back open."

Christie estimated 39,000 New Jersey families remain displaced, down from 161,000 the day after the storm. In New York, more than 250 families are still living in hotel rooms across New York paid for by the Federal Emergency Management Agency, while others are still shacking up with relatives or living in temporary rentals.

Everyone simply wants to make their homes livable again, said Ray Marten, whose home in the Belle Harbor section of New York City's Queens borough burned down when a fire swept along his street during the storm, and whose family of six is renting a nearby house.

"If you go up my block now, all the houses have been demolished and removed," Marten said. "They're pretty much just holes in the ground. Sand pits."

Separation is the new reality for the Gatti family, a clan of several generations that shared the same three-story home near the ocean on Staten Island until Sandy destroyed it. The flood-soaked place was demolished months ago, and they're waiting for a government buyout. Now the family is scattered across New Jersey, New York and Texas.

"The whole family's separated," said Marge Gatti, the matriarch. "And it's terrible, you know?"

Her son, Anthony, recently drove a U-Haul packed with his meager belongings to Killeen, Texas, where he will start a new life as a car mechanic.

"Mentally, I'm not all that well in the head," said Anthony Gatti, who slept in a tent in front of the ruined home for weeks after the storm. "I know I've got to get some kind of help. I can't seem to shake it out of my life."

Ginjer Doherty was 9 years old when Sandy bubbled up through the floor of her Middletown, N.J., home and ripped the front wall off it. She and her parents went to a firehouse a few days later to see Christie talk about what was being done to recover.

The governor comforted Ginjer, telling her she would be all right, that the grown-ups were on top of things and would take care of her. Ginjer recently had an essay published in Time magazine recalling the encounter and describing her life after Sandy.

"My house was all messed up, and people told us we couldn't stay there anymore," she wrote. "The governor told me not to worry ? that my parents would take care of everything ? and he looked very serious and sad, and he cried.

"Things are going O.K. for my family," she wrote. "We want to go back home, but rebuilding is going to take a long time. But we have a place to live for now. I even rescued a cat that was homeless after Sandy; I wanted him to be safe and loved like I feel."

In an interview with The Associated Press, Ginjer, now 10, said she is sad that her home won't be ready until October; her mom says it has been gutted and needs to be elevated.

Of the delay, Ginjer said simply, "It stinks."

Sandy also damaged interior areas, particularly those along rivers in northern New Jersey. Cities including Hoboken and Jersey City were inundated, and officials continue try seek exemptions for skyscrapers and large apartments from federal rules requiring flood-prone buildings to be elevated. George Stauble, whose Little Ferry house took in four feet of water, said FEMA payouts caused some rifts between neighbors.

"Everybody's house had pretty much the same amount of damage, but people are getting different amounts of money, and that's caused some problems," he said, adding some homeowners received as little as $8,000, while others received as much as $29,000.

___

Contributing to this report were Associated Press writers Meghan Barr and Deepti Hajela in New York and David Porter in Little Ferry, N.J.

___

Wayne Parry can be reached at http://twitter.com/WayneParryAC.

Source: http://news.yahoo.com/6-months-sandy-thousands-homeless-ny-nj-154507020.html

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Saturday, April 27, 2013

Wednesday, April 24, 2013

6 NY pols being arraigned on corruption charges

WHITE PLAINS, N.Y. (AP) ? Six politicians are up for arraignment in a case that alleges an audacious plot to buy a spot on New York City's mayoral ballot.

Defense lawyers say that not-guilty pleas are expected from all six on Tuesday.

The case has spawned several proposals to fight corruption in New York.

State Sen. Malcolm Smith, a Democrat, is accused of scheming to bribe county Republican leaders for the GOP line on this year's mayoral ballot.

The indictment says New York City Councilman Daniel Halloran, a Republican, was in on the plot. And it says two party leaders accepted tens of thousands of dollars in bribes.

In a separate scheme, the mayor and deputy mayor of suburban Spring Valley are accused of taking bribes to approve a real estate project.

Source: http://news.yahoo.com/6-ny-pols-being-arraigned-corruption-charges-061912446.html

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Change diet, exercise habits at same time for best results, study says

Apr. 21, 2013 ? Most people know that the way to stay healthy is to exercise and eat right, but millions of Americans struggle to meet those goals, or even decide which to change first.

Now, researchers at the Stanford University School of Medicine have discovered that focusing on changing exercise and diet at the same time gives a bigger boost than tackling them sequentially. They also found that focusing on changing diet first -- an approach that many weight-loss programs advocate -- may actually interfere with establishing a consistent exercise routine.

Their findings were published online April 21in the Annals of Behavioral Medicine.

"It may be particularly useful to start both at the same time," said Abby King, PhD, lead author of the study and a professor of health research and policy and of medicine. "If you need to start with one, consider starting with physical activity first."

The few published studies on how to introduce more than one shift in healthy habits report conflicting findings -- and few have looked at exercise and dietary change together. In examining the issue, the researchers also wanted to study people who specifically complained that the demands of their schedules didn't give them enough time to make healthy dietary and exercise choices. The reasoning was that if successful programs could be developed for these time-strapped individuals, they would likely work for others, as well.

Researchers split 200 initially inactive participants, ages 45 and older and with suboptimal diets, into four different groups. Each group received a different kind of telephone coaching. The first group learned to make changes to diet and exercise at the same time. The second group learned to make dietary changes first and didn't try changing their exercise habits until a few months later. The third group reversed that order and learned to change exercise habits before adding healthy dietary advice. The fourth group, for comparison, did not make any dietary or exercise changes, but was taught stress-management techniques. Researchers tracked participants' progress in all four groups for a year.

Despite the challenge of making multiple changes to their already-busy routines at once, those who began changing diet and exercise habits at the same time were most likely to meet national guidelines for exercise -- 150 minutes per week -- and nutrition: five to nine servings of fruit and vegetables daily, and keeping calories from saturated fats at 10 percent or less of their total intake.

Those who started with exercise first did a good job of meeting both the exercise and diet goals, though not quite as good as those who focused on diet and exercise simultaneously.

The participants who started with diet first did a good job meeting the dietary goals but didn't meet their exercise goals. King, who also is a senior researcher at the Stanford Prevention Research Center, speculates this is because changing diet and introducing exercise both have unique challenges. "With dietary habits, you have no choice; you have to eat," she said. "You don't have to find extra time to eat because it's already in your schedule. So the focus is more on substituting the right kinds of food to eat."

But, she said, finding time for exercise if you already have a busy schedule can be challenging. She pointed out that even the most successful group, those receiving the two behavioral health programs simultaneously, lagged behind in meeting the physical activity goal at first, though over the course of a year were eventually able to meet it.

King credits the way health educators explained the dietary and exercise advice to participants for their overall success and the study's high retention rate. They met with participants in person just once at the beginning of the one-year period. After that, they called once a month, spending as little as 10 to 15 minutes -- and no more than 40 minutes -- providing advice and support for diet and exercise.

For the participants, whose schedules and stressful lives had previously interfered with making healthy lifestyle choices, this approach worked, King said. She said that telephoning participants was a convenient and flexible way to provide personalized information. "These health behaviors aren't things that we change over a six-week period and then our job is done," she said. "They're things that people grapple with their whole lives, so to develop 'touches' of advice and support in a cost-efficient way is becoming more and more important."

Participants in this study were not actively trying to lose weight, just trying to develop healthy habits. King's next step is to test the same sequential-versus-simultaneous approaches among people who are trying to lose weight.

Other Stanford authors of the study include senior research scholar Cynthia Castro, PhD; statistical analyst David Ahn, PhD; and former postdoctoral scholars Matthew Buman, PhD, and Eric Hekler, PhD, (who are both now at Arizona State University) and Guido Urizar, PhD (now at Cal State Long Beach).

The study was supported by the National Institute on Aging (grant R01AG21010) and the National Heart, Lung and Blood Institute (grant 5T32HL007034).

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The above story is reprinted from materials provided by Stanford University Medical Center. The original article was written by Rina Shaikh-Lesko.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. King AC et al. Behavioral Impacts of Sequentially versus Simultaneously Delivered Dietary Plus Physical Activity Interventions: the CALM Trial. Annals of Behavioral Medicine, 2013 DOI: 10.1007/s12160-013-9501-y

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/nutrition/~3/gooWPdOXUec/130422101300.htm

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Tuesday, April 23, 2013

Iran denies link with Canada terror plot suspects

TEHRAN, Iran (AP) ? Iran on Tuesday denied any links with an alleged terrorist plot that Canadian authorities claim was directed by al-Qaida operatives in Iran and sought to derail a passenger train.

Canadian authorities allege the suspects Chiheb Esseghaier, 30, and Raed Jaser, 35, had "direction and guidance" from al-Qaida members in Iran, though there were no claims the planned attacks were state-sponsored by Tehran. Esseghaier is believed to be Tunisian and Jaser from the United Arab Emirates.

Some al-Qaida members had been allowed to stay in Iran after fleeing Afghanistan, but were under tight Iranian controls. Relations have been rocky between mainly Shiite Iran and the Sunni-led al-Qaida on many fronts for years.

Iran was a strong opponent of the Taliban, which sheltered Osama bin Laden and others before the U.S.-led invasion after the Sept. 11, 2001, attacks. Many al-Qaida leaders also view Shiite Muslims with suspicion and hostility.

Iran's Foreign Ministry spokesman Ramin Mehmanparast told reporters that there is "no firm evidence" of any Iranian involvement and groups such as al-Qaida have "no compatibility with Iran in both political and ideological fields."

"We oppose any terrorist and violent action that would jeopardize lives of innocent people," said Mehmanparast.

He called the Canadian claims part of hostile policies against Tehran, and accused Canada of indirectly aiding al-Qaida by joining Western support for Syrian rebels. Some Islamic militant factions, claiming allegiance to al-Qaida, have joined forces seeking to topple the regime of Bashar Assad, one of Iran's main allies in the region.

"The same (al-Qaida) current is killing people in Syria while enjoying Canada's support," said Mehmanparast.

In a separate comment, Iranian Foreign Minister Ali Akbar Salehi called the claim by Canadian authorities "the most ridiculous fake words."

"I hope Canadian officials resort to more wisdom," he said.

The two countries have no diplomatic relations after Canada unilaterally closed its embassy in Tehran in 2012 and expelled Iranian diplomats from Ottawa.

On Monday, Alireza Miryousefi, spokesman for the Iranian mission to the United Nations, said the terrorist network was not operating in Iran.

"Iran's position against this group is very clear and well known. (Al-Qaida) has no possibility to do any activity inside Iran or conduct any operation abroad from Iran's territory," Miryousefi said in a statement emailed to The Associated Press. "We reject strongly and categorically any connection to this story."

Source: http://news.yahoo.com/iran-denies-canada-terror-plot-suspects-083030339.html

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Now may land on Google's home page, come to the web

Now may land on Google's home page

While everyone else speculates about new Nexii and what sweet treat the next version of Android will be named after, we're anticipating some exciting news about Now at Google I/O. Specifically, that it might be coming to both iOS and the desktop. We've already seen quite a bit of evidence that the virtual assistant app will eventually land on Apple's mobile platform and maybe even Chrome. Newly discovered code in a Google page hints that it might just become part of the standard web search interface -- provided you opt to turn it on, of course. Source code for the page in testing encourages you to, "get started with Google Now," because it provides, "just the right information at just the right time." It also offers you the opportunity to change you home and work locations because, as the explanation goes, "Google Now uses your Home location to show relevant information like weather, traffic conditions, and nearby places." As you dig through you'll also find plenty of references to "now_card."

If Now becomes a standard part of the Mountain View lineup, regardless of platform, it could be huge for a company which already dominates the search market. Not to mention, it might satiate those seven people out there still mourning the loss of iGoogle. We won't know anything for sure until the wraps are taken off and have reached out to the company for comment, but we anticipate the response will be predictably non-committal.

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Source: Google Operating System, Google

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/lGEH6i6vxok/

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Tuesday, April 16, 2013

Nanosponges soak up toxins released by bacterial infections and venom

Monday, April 15, 2013

Engineers at the University of California, San Diego have invented a "nanosponge" capable of safely removing a broad class of dangerous toxins from the bloodstream ? including toxins produced by MRSA, E. coli, poisonous snakes and bees. These nanosponges, which thus far have been studied in mice, can neutralize "pore-forming toxins," which destroy cells by poking holes in their cell membranes. Unlike other anti-toxin platforms that need to be custom synthesized for individual toxin type, the nanosponges can absorb different pore-forming toxins regardless of their molecular structures. In a study against alpha-haemolysin toxin from MRSA, pre-innoculation with nanosponges enabled 89 percent of mice to survive lethal doses.

Administering nanosponges after the lethal dose led to 44 percent survival.

The team, led by nanoengineers at the UC San Diego Jacobs School of Engineering, published the findings in Nature Nanotechnology April 14.

"This is a new way to remove toxins from the bloodstream," said Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering and the senior author on the study. "Instead of creating specific treatments for individual toxins, we are developing a platform that can neutralize toxins caused by a wide range of pathogens, including MRSA and other antibiotic resistant bacteria," said Zhang. The work could also lead to non-species-specific therapies for venomous snake bites and bee stings, which would make it more likely that health care providers or at-risk individuals will have life-saving treatments available when they need them most.

The researchers are aiming to translate this work into approved therapies. "One of the first applications we are aiming for would be an anti-virulence treatment for MRSA. That's why we studied one of the most virulent toxins from MRSA in our experiments," said "Jack" Che-Ming Hu, the first author on the paper. Hu, now a post-doctoral researcher in Zhang's lab, earned his Ph.D. in bioengineering from UC San Diego in 2011.

Aspects of this work will be presented April 18 at Research Expo, the annual graduate student research and networking event of the UC San Diego Jacobs School of Engineering.

Nanosponges as Decoys

In order to evade the immune system and remain in circulation in the bloodstream, the nanosponges are wrapped in red blood cell membranes. This red blood cell cloaking technology was developed in Liangfang Zhang's lab at UC San Diego. The researchers previously demonstrated that nanoparticles disguised as red blood cells could be used to deliver cancer-fighting drugs directly to a tumor. Zhang also has a faculty appointment at the UC San Diego Moores Cancer Center.


Engineers at the University of California, San Diego have invented a ?nanosponge? capable of safely removing a broad class of dangerous toxins from the bloodstream -- including toxins produced by MRSA, E. coli, poisonous snakes and bees. These nanosponges, which thus far have been studied in mice, can neutralize ?pore-forming toxins,? which destroy cells by poking holes in their cell membranes. Unlike other anti-toxin platforms that need to be custom synthesized for individual toxin type, the nanosponges can absorb different pore-forming toxins regardless of their molecular structures. In a study against alpha-haemolysin toxin from MRSA, pre-innoculation with nanosponges enabled 89 percent of mice to survive lethal doses. Administering nanosponges after the lethal dose led to 44 percent survival. Credit: UC San Diego Jacobs School of Engineering

Red blood cells are one of the primary targets of pore-forming toxins. When a group of toxins all puncture the same cell, forming a pore, uncontrolled ions rush in and the cell dies.

The nanosponges look like red blood cells, and therefore serve as red blood cell decoys that collect the toxins. The nanosponges absorb damaging toxins and divert them away from their cellular targets. The nanosponges had a half-life of 40 hours in the researchers' experiments in mice. Eventually the liver safely metabolized both the nanosponges and the sequestered toxins, with the liver incurring no discernible damage.

Each nanosponge has a diameter of approximately 85 nanometers and is made of a biocompatible polymer core wrapped in segments of red blood cells membranes.

Zhang's team separates the red blood cells from a small sample of blood using a centrifuge and then puts the cells into a solution that causes them to swell and burst, releasing hemoglobin and leaving RBC skins behind. The skins are then mixed with the ball-shaped nanoparticles until they are coated with a red blood cell membrane.

Just one red blood cell membrane can make thousands of nanosponges, which are 3,000 times smaller than a red blood cell. With a single dose, this army of nanosponges floods the blood stream, outnumbering red blood cells and intercepting toxins.

Based on test-tube experiments, the number of toxins each nanosponge could absorb depended on the toxin. For example, approximately 85 alpha-haemolysin toxin produced by MRSA, 30 stretpolysin-O toxins and 850 melittin monomoers, which are part of bee venom.

In mice, administering nanosponges and alpha-haemolysin toxin simultaneously at a toxin-to-nanosponge ratio of 70:1 neutralized the toxins and caused no discernible damage.

One next step, the researchers say, is to pursue clinical trials.

###

University of California - San Diego: http://www.ucsd.edu

Thanks to University of California - San Diego for this article.

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Source: http://www.labspaces.net/127740/Nanosponges_soak_up_toxins_released_by_bacterial_infections_and_venom

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Monday, April 15, 2013

Alicia Keys campaigns for HIV education

WASHINGTON (AP) ? Alicia Keys says she wants to spark a global conversation about HIV, the virus that causes AIDS.

The Grammy Award-winning singer says that when she traveled to Africa and India she felt connected to women with the virus because "they looked like they could be my sister, or they could be my aunt, or they could be my cousin."

Keys is working with the Kaiser Family Foundation for "Empowered," a campaign launched last month to educate women about HIV and provide grants to community-based projects that will do that.

According to Kaiser, one in four of the 1.1 million people living with HIV in the United States are women. Women of color account for about two-thirds of new HIV infections among women.

The campaign includes outreach through public service ads, social media and community programs. It encourages women to learn about HIV and AIDS, talk with family and friends, protect themselves and loved ones, get tested, prevent spreading the disease and stay on treatment.

Keys is also leading the Empowered Community Grants program with Kaiser and AIDS United that will give up to $25,000 grants to community-based projects that focus on women and HIV.

The campaign is scheduled to run for five years and publish a report annually on women's experiences with HIV/AIDS and examine cultural changes regarding education, misconceptions and the stigma associated with the disease.

Keys is co-founder of Keep a Child Alive, which provides AIDS treatment, food and other support to children and families affected by HIV and AIDS in Africa and India.

Source: http://news.yahoo.com/alicia-keys-campaigns-hiv-education-191441302.html

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Thursday, April 11, 2013

Despite talk of imminent attack, calm in NKorea

A North Korean commuter crosses a street in central Pyongyang on Wednesday, April 10, 2013. (AP Photo/David Guttenfelder)

A North Korean commuter crosses a street in central Pyongyang on Wednesday, April 10, 2013. (AP Photo/David Guttenfelder)

An apartment block stands among the buildings at dawn in central Pyongyang, North Korea, Wednesday, April 10, 2013. (AP Photo/David Guttenfelder)

A South Korean army soldier uses his radio at barricaded Unification Bridge near the border village of Panmunjom, that has separated the two Koreas since the Korean War, in Paju, north of Seoul, South Korea, Wednesday, April 10, 2013. A few hundred South Korean managers, some wandering among quiet assembly lines, were all that remained Tuesday at the massive industrial park run by the rival Koreas after North Korea pulled its more than 50,000 workers from the complex. Other managers stuffed their cars full of finished goods before heading south across the Demilitarized Zone that divides the nations. (AP Photo/Lee Jin-man)

A North Korean soldier stands beneath roadside propaganda which reads "Let's Uphold the Military First Revolutionary Leadership of the Great Comrade Kim Jong Un With Loyalty" in Pyongyang on Tuesday, April 9, 2013. (AP Photo/David Guttenfelder)

Visitors look over the North-South Korea industrial complex in Kaesong, North Korea, through binoculars at Dora Observation Post in the demilitarized zone (DMZ) near the border village of Panmunjom, in Paju, South Korea, Tuesday, April 9, 2013. The massive industrial park the rival Koreas have jointly run for nearly decade was a virtual ghost town Tuesday, its South Korean managers left to wander past shutdown assembly lines or stuff their cars to the brim with whatever goods would fit before heading south for the Demilitarized Zone that divides the nations. (AP Photo/Won Dae-hyun) KOREA OUT

(AP) ? The prospect of a North Korean missile launch is "considerably high," South Korea's foreign minister told lawmakers Wednesday as Pyongyang prepared to mark the April 15 birthday of its founder, historically a time when it seeks to draw the world's attention with dramatic displays of military power.

The missile is expected to be a medium-range Musudan missile with a range of 3,500 kilometers (2,180 miles) capable of flying over Japan, Foreign Minister Yun Byung-se told lawmakers in Seoul. Earlier a Defense Ministry official said preparations appeared to be complete, and that the launch could take place at any time.

North Korean officials have not announced plans to launch a missile, but have told foreign diplomats in Pyongyang that it will not be able to guarantee their safety starting Wednesday. It has also urged tourists in South Korea to take cover, warning a nuclear war was imminent. However, most diplomats and foreign residents appeared to be staying put.

Such threats are, however, seen as rhetoric and an attempt by North Korea to scare foreigners into pressing their governments to pressure Washington and Seoul to change their policies toward Pyongyang, and to boost the military credentials of its young leader, Kim Jong Un.

On the streets of Pyongyang, however, the focus was less on preparing for war and more on beautifying the city ahead of the nation's biggest holiday. Soldiers hammered away on construction projects, gardeners got down on their knees to plant flowers and trees, and students marched off to school, belying the high tensions.

Last year, the days surrounding the centennial of the birth of Kim Il Sung, grandfather of the current ruler, was marked by parades of tanks, goose-stepping soldiers and missiles, as well as the failed launch of a satellite-carrying rocket widely believed by the U.S. and its allies in the West to be a test of ballistic missile technology. A subsequent test in December went off successfully, and that was followed by the country's third underground nuclear test on Feb. 12 this year, possibly taking the regime closer to mastering the technology for mounting an atomic bomb on a missile.

The resulting U.N. sanctions and this spring's annual U.S.-South Korean military drills have been met with an unending string of threats and provocations from the North.

Adm. Samuel Locklear, commander of U.S. Pacific Command, told the Senate Armed Services Committee in Washington on Tuesday that North Korea's persistent nuclear and missile programs and threats have created "an environment marked by the potential for miscalculation."

He said the U.S. military and its allies would be ready if North Korea tries to strike.

The Musadan is a ballistic missile, and South Korea says its launch would violate a U.N. Security Council resolution banning any ballistic activity by North Korea.

Despite such tidings of war, the people of Pyongyang went about their daily lives.

Associated Press journalists in the North Korean capital saw soldiers wearing hard hats rumbling past in the back of a truck as they prepared for another day's work doing construction. In recent years, military personnel have been pressed into helping build the many urban renewal projects that have been prioritized since Kim Jong Un came to power in December 2011.

In a sign they have been diverted away from preparing for conventional warfare, they are commonly referred to as "soldier-builders," and are also called upon to help plant and harvest rice and other crops in a nation that suffers from chronic food shortages.

North Korea sporadically holds civil air raid drills during which citizens practice blacking out their windows and seeking shelter. But no such drills have been held in recent months, local residents said.

"I'm not at all worried. We have confidence in our young marshal" Kim Jong Un, a cleaning lady at the Koryo Hotel said as she made up a guest's bed. "The rest of the world can just squawk all they want but we have confidence in his leadership.

"We are resolved to stay and defend him until the end," she said. "It may be hard for the rest of the world to understand, and those who are worried are welcome to leave," she said in typically nationalistic language.

But there was no sign of an exodus of foreigners from Seoul or Pyongyang. Britain and other governments with embassies in Pyongyang said they had no immediate plans to withdraw but would continue assessing the situation.

North Korea has been escalating tensions with the U.S. and South Korea, its wartime foes, for months. The tightened U.N. sanctions that followed the nuclear test drew the ire of North Korea, which accused Washington and Seoul of leading the campaign against it. Annual U.S.-South Korean military drills south of the border have further incensed Pyongyang, which sees them as practice for an invasion.

Last week, Kim Jong Un enshrined the pursuit of nuclear weapons ? which the North characterizes as a defense against the U.S. ? as a national goal, along with improving the economy. North Korea also declared it would restart a mothballed nuclear complex.

Citing the tensions with Seoul, North Korea on Monday pulled more than 50,000 workers from the Kaesong industrial park, which combines South Korean technology and know-how with cheap North Korean labor. It was the first time that production was stopped at the decade-old factory park, the only remaining symbol of economic cooperation between the Koreas.

Pyongyang also has moved to its eastern seaboard what is believed by U.S. and South Korean intelligence to be a mid-range missile capable of hitting targets in Japan, such as the U.S. military installations on that country's main island, as well as the U.S. territory of Guam. South Korean officials say North Korea will likely test-fire the missile into the sea as a display of its military prowess.

The United States and South Korea have raised their defense postures, as has Japan, which deployed PAC-3 missile interceptors in key locations around Tokyo. And Locklear said the U.S. military would be ready to strike back if provoked.

One historian, James Person, noted that it isn't the first time North Korea has warned foreign embassies to prepare for a U.S. attack.

He said that in 1968, following North Korea's seizure of an American ship, the USS Pueblo, Pyongyang persistently advised foreign diplomats to prepare for a U.S. counterattack. Cables from the Romanian mission in Pyongyang showed embassies were instructed to build anti-air bunkers "to protect foreigners against air attacks," he said.

The cables were obtained and posted online by the Wilson Center's North Korea International Documentation Project.

Person called it one of North Korea's first forays into what he dubs "military adventurism."

"In 1968, there was some concern there would be an attack, but (the North Koreans) certainly were building it up to be more than it was in hopes of getting more assistance from their allies at the time," Person said by phone from Alexandria, Virginia.

"I think much of it was hot air then. Today, I think again it's more hot air," he said. "The idea is to scare people into pressuring the United States to return to negotiations with North Korea. That's the bottom line."

___

Associated Press writers Hyung-jin Kim in Seoul, South Korea, Nicole Winfield in Rome and Matthew Pennington, Donna Cassata and Richard Lardner in Washington contributed to this report.

___

Follow AP's Korea bureau chief on Twitter at twitter.com/newsjean.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-04-10-Koreas-Tension/id-5e0bfc648b7249b8972a4d93147b1700

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Tuesday, April 9, 2013

Wall Street set to rise after year's worst week

By Leah Schnurr

NEW YORK (Reuters) - Wall Street was set to open modestly higher on Monday, bouncing back from the worst weekly decline this year even as investors face the prospect of a lackluster corporate earnings season.

Earnings forecasts have been scaled back heading into first-quarter reports. S&P 500 earnings are expected to have risen just 1.6 percent from a year ago, according to Thomson Reuters data, down from a 4.3 percent forecast in January.

Worries on Friday about the pace of earnings growth was a factor in Wall Street racking up its worst week this year so far, while a weaker-than-expected jobs report prompted concern the U.S. economy is in a slow patch.

Despite those headwinds, the loose monetary policy from central banks around the world continues to attract investors to equities, said Peter Cardillo, chief market economist at Rockwell Global Capital in New York.

"It's all about easy money and it's lifting equities around the globe at this time," said Cardillo.

The Bank of Japan started its bond purchases after it announced last week it will inject about $1.4 trillion into the economy in less than two years.

In the United States, the Federal Reserve's bond buying program has been a significant catalyst of the recent rally that has sent major indexes to record levels.

Still, U.S. markets could see a technical correction of about 6 percent to 8 percent in the latter part of the month as the focus turns to corporate results, said Cardillo.

JPMorgan Chase and Bed Bath and Beyond are among the major companies set to announce results later in the week, while Alcoa's earnings will be the first from a Dow component after Monday's closing bell.

The S&P 500 is up nearly 9 percent for the year so far, while the Dow has gained more than 11 percent.

S&P 500 futures rose 4.9 points and were above fair value, a formula that evaluates pricing by taking into account interest rates, dividends and time to expiration on the contract. Dow Jones industrial average futures gained 18 points, and Nasdaq 100 futures added 9.5 points.

Fed Chairman Ben Bernanke will give a speech later on Monday after markets are closed. Investors have been watching for any insight into the Fed's thinking on how long the central bank will keep its asset purchase program in place as it tries to boost the economic recovery.

General Electric Co said it will buy oilfield services provider Lufkin Industries Inc for about $3.3 billion, sending Lufkin shares up 37.5 percent to $87.95 in premarket trade. GE edged up 0.3 percent at $23.00.

Investors will be keeping an eye on the latest developments out of the euro zone after a constitutional court in Portugal overturned key austerity measures in the government's latest budget. Portugal's prime minister said the government will cut spending to meet targets agreed with its lenders.

(Editing by Kenneth Barry)

Source: http://news.yahoo.com/futures-last-weeks-sell-off-113132002--sector.html

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'Pharmaceutical' approach boosts oil production from algae

Apr. 8, 2013 ? Taking an approach similar to that used for discovering new therapeutic drugs, chemists at the University of California, Davis, have found several compounds that can boost oil production by green microscopic algae, a potential source of biodiesel and other "green" fuels.

The work appears online in the journal Chemical Biology.

Microalgae are single-celled organisms that, like green plants, use photosynthesis to capture carbon dioxide and turn it into complex compounds, including oils and lipids. Marine algae species can be raised in saltwater ponds and so do not compete with food crops for land or fresh water.

"They can live in saltwater, they take sunlight and carbon dioxide as a building block, and make these long chains of oil that can be converted to biodiesel," said Annaliese Franz, assistant professor of chemistry and an author of the paper.

Franz, graduate students Megan Danielewicz, Diana Wong and Lisa Anderson, and undergraduate student Jordan Boothe screened 83 compounds for their effects on growth and oil production in four strains of microalgae. They identified several that could boost oil production by up to 85 percent, without decreasing growth.

Among the promising compounds were common antioxidants such as epigallocatechin gallate, found in green tea, and butylated hydroxyanisole (BHA), a common food preservative.

The team has carried out growth experiments in culture volumes of up to half a liter. They calculate that some of the chemicals they analyzed would be cost-effective when scaled up to a 50,000 liter pond. After oils have been extracted from the algae, the remaining mass can be processed for animal feed or other uses.

Franz came to UC Davis in 2007 with a background in pharmaceutical chemistry. Given the campus's emphasis on biofuels, she started thinking about applying high-throughput techniques used to screen for new drugs to looking for compounds that could affect microalgae.

The idea, Franz said, is to look for small molecules that can affect a metabolic pathway in a cell. By setting up large numbers of cell cultures and measuring a simple readout in each, it's possible to screen for large numbers of different compounds in a short time and home in on the most promising.

"The basic concept comes from the pharmaceutical industry, and it's been used for human cells, plants, yeast, but not so far for algae," she said.

"There are many cases where small molecules are having an effect to treat a disease, so it makes sense that if you can affect a pathway in a human for a disease, you can affect a pathway in an algal cell," Franz said.

Patents on the work are pending. The research was funded by Chevron Technology Ventures through a cooperative agreement with UC Davis.

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The above story is reprinted from materials provided by University of California - Davis.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Annaliese K. Franz, Megan A. Danielewicz, Diana M. Wong, Lisa A. Anderson, Jordan R. Boothe. Phenotypic Screening with Oleaginous Microalgae Reveals Modulators of Lipid Productivity. ACS Chemical Biology, 2013; : 130322131504001 DOI: 10.1021/cb300573r

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/J5Iv6vVkoLQ/130408152951.htm

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